{"id":13027,"date":"2023-07-24T23:06:35","date_gmt":"2023-07-24T21:06:35","guid":{"rendered":"https:\/\/tirzepatyd.eu\/?post_type=product&#038;p=13027"},"modified":"2026-04-18T11:31:05","modified_gmt":"2026-04-18T09:31:05","slug":"tirzepatide-5mg","status":"publish","type":"product","link":"https:\/\/tirzepatyd.eu\/en\/shop-product\/tirzepatide-5mg\/","title":{"rendered":"GLP1+GIP 5 mg vial"},"content":{"rendered":"<div data-elementor-type=\"product-post\" data-elementor-id=\"13027\" class=\"elementor elementor-13027\" data-elementor-post-type=\"product\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ba8b07b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ba8b07b\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-08e6d01\" data-id=\"08e6d01\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-377f1fb elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"377f1fb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h2 data-start=\"207\" data-end=\"267\">Tirzepatide 5mg - structural characteristics<\/h2><p data-start=\"316\" data-end=\"828\"><span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">Tirzepatide 5mg<\/span><\/span> is a synthetic peptide analog designed as a dual agonist of GIPR and GLP-1R receptors. The molecule consists of an amino acid sequence optimized for enzymatic stability and extended half-life. The structural modifications used, including amino acid substitutions and coupling to the lipid chain, allow reversible binding to albumin, which reduces renal clearance and increases stability in the biological environment.<\/p><p data-start=\"830\" data-end=\"984\">Spectrometric and chromatographic (HPLC\/UPLC) analyses used for quality control confirm the high purity of the substance used in the study.<\/p><hr data-start=\"986\" data-end=\"989\" \/><h2 data-start=\"112\" data-end=\"167\">Mechanism of receptor action - Tirzepatide 5mg<\/h2><p data-start=\"169\" data-end=\"545\"><span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">Tirzepatide<\/span><\/span> at a dose of 5 mg shows agonist activity against two key incretin receptors belonging to the GPCR family - GIPR and GLP-1R - in research models. Dual activation of these pathways leads to an integrated metabolic response, including both regulation of glucose metabolism and modulation of energy balance.<\/p><p data-start=\"547\" data-end=\"584\">At the cellular level, it is observed:<\/p><ul><li data-start=\"588\" data-end=\"631\">An increase in intracellular cAMP concentration,<\/li><li data-start=\"634\" data-end=\"680\">Increased glucose-dependent insulin secretion,<\/li><li data-start=\"683\" data-end=\"743\">Regulation of glucagon secretion under hyperglycemic conditions,<\/li><li data-start=\"746\" data-end=\"781\">Slowing down gastric emptying,<\/li><li data-start=\"784\" data-end=\"843\">Effects on central satiety mechanisms within the hypothalamus.<\/li><\/ul><p data-start=\"845\" data-end=\"1240\">In clinical studies, activation of the GIP\/GLP-1 axis has been shown to be associated with changes in body weight parameters, including fat reduction and improved metabolic indices. This mechanism is interpreted as a synergistic effect resulting from the simultaneous modulation of several key hormonal pathways responsible for regulating appetite, energy intake and substrate metabolism.<\/p><p data-start=\"1242\" data-end=\"1430\">The 5-mg dose was one of the benchmarks in the dose-effect analyses, allowing assessment of the pharmacodynamic profile and tolerability under controlled study conditions.<\/p><hr data-start=\"1502\" data-end=\"1505\" \/><h2 data-start=\"1507\" data-end=\"1553\">Effects on metabolic parameters in studies<\/h2><p data-start=\"1555\" data-end=\"1834\">In the study <strong data-start=\"1565\" data-end=\"1579\">SURMOUNT-1<\/strong> published in <span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">New England Journal of Medicine<\/span><\/span> (2022) <strong>reported an average weight reduction of about 15% at the 5 mg dose after 72 weeks of follow-up<\/strong>. Changes in waist circumference, lipidogram and markers of insulin resistance were also included in the analyses.<\/p><p data-start=\"1836\" data-end=\"1996\">The SURPASS program evaluated the effect of tirzepatydu on HbA1c in patients with type 2 diabetes, showing a statistically significant reduction relative to comparative therapies.<\/p><hr data-start=\"1998\" data-end=\"2001\" \/><h2 data-start=\"2003\" data-end=\"2051\">Thirzepatide 5mg as a laboratory reagent<\/h2><p data-start=\"2053\" data-end=\"2137\">In the research community, formulations based on the tirzepatydu molecule are used as:<\/p><ul><li data-start=\"2141\" data-end=\"2204\">reference material for incretin receptor studies,<\/li><li data-start=\"2207\" data-end=\"2247\">GPCR signaling analysis tool,<\/li><li data-start=\"2250\" data-end=\"2332\">Pharmacological model in energy homeostasis regulation projects.<\/li><\/ul><p data-start=\"2334\" data-end=\"2429\">The substance is intended for research and analytical use only (Research Use Only).<\/p><hr data-start=\"2431\" data-end=\"2434\" \/><h2 data-start=\"2436\" data-end=\"2456\">Online availability and where to buy Tirzepatide 5 mg<\/h2><p data-start=\"2458\" data-end=\"2802\">Reference materials defined as tirzepatide 5 mg can be offered by specialized chemical reagent suppliers. Verification should include quality documentation (CoA, HPLC profile), storage conditions and RUO determination. Does not constitute a product for clinical use outside of approved studies.<\/p><hr data-start=\"2431\" data-end=\"2434\" \/><p data-start=\"2458\" data-end=\"2802\"><a href=\"https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/5mg-1ml-Camera.png\"><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-30656 size-medium\" src=\"https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/5mg-1ml-Camera-300x225.png\" alt=\"Tirzepatide 5 mg is a synthetic GIP\/GLP-1 peptide analog intended for research applications.\" width=\"300\" height=\"225\" srcset=\"https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/5mg-1ml-Camera-300x225.png 300w, https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/5mg-1ml-Camera-800x600.png 800w, https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/5mg-1ml-Camera-64x48.png 64w, https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/5mg-1ml-Camera-768x576.png 768w, https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/5mg-1ml-Camera-16x12.png 16w, https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/5mg-1ml-Camera.png 1024w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p><p><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10107501\/\">Source:<\/a><\/p><hr data-start=\"2431\" data-end=\"2434\" \/><p><strong>Product intended for scientific research and laboratory analysis. All articles and information on this site are for informational and educational purposes only.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p><strong data-start=\"169\" data-end=\"189\">GLP1+GIP 5mg (Tirzepatide 5mg)<\/strong> is a high-purity synthetic peptide designed as a dual agonist of GIP and GLP-1 receptors, used in advanced research projects on incretin metabolism and signaling.<\/p>","protected":false},"featured_media":30656,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[124,111,15],"product_tag":[136],"class_list":{"0":"post-13027","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-produkty-w-fiolce","7":"product_cat-glp1gip","8":"product_cat-laboratory-research","9":"product_tag-fiolka","11":"first","12":"instock","13":"shipping-taxable","14":"purchasable","15":"product-type-variable"},"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/product\/13027","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/comments?post=13027"}],"version-history":[{"count":27,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/product\/13027\/revisions"}],"predecessor-version":[{"id":35467,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/product\/13027\/revisions\/35467"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/media\/30656"}],"wp:attachment":[{"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/media?parent=13027"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/product_brand?post=13027"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/product_cat?post=13027"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/product_tag?post=13027"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}