{"id":11835,"date":"2023-04-16T00:40:42","date_gmt":"2023-04-15T22:40:42","guid":{"rendered":"https:\/\/tirzepatyd.eu\/?page_id=11835"},"modified":"2025-12-16T05:05:23","modified_gmt":"2025-12-16T04:05:23","slug":"tirzepatide","status":"publish","type":"page","link":"https:\/\/tirzepatyd.eu\/en\/tirzepatide\/","title":{"rendered":"Tirzepatide"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"11835\" class=\"elementor elementor-11835\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ba19006 e-con-full e-flex e-con e-parent\" data-id=\"ba19006\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-debb04e e-flex e-con-boxed e-con e-child\" data-id=\"debb04e\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-ae058b9 e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"ae058b9\" data-element_type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2edbf0b elementor-widget elementor-widget-heading\" data-id=\"2edbf0b\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Thirzepatide - how does it work?<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ddb96e3 e-flex e-con-boxed e-con e-parent\" data-id=\"ddb96e3\" data-element_type=\"container\" data-settings=\"{&quot;shape_divider_top&quot;:&quot;tilt&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-shape elementor-shape-top\" aria-hidden=\"true\" data-negative=\"false\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewbox=\"0 0 1000 100\" preserveaspectratio=\"none\">\n\t<path class=\"elementor-shape-fill\" d=\"M0,6V0h1000v100L0,6z\"\/>\n<\/svg>\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1f971a5 e-con-full e-flex e-con e-child\" data-id=\"1f971a5\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-398f39f elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"398f39f\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Peptide incretin receptor agonists<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ab9f111 elementor-invisible elementor-widget elementor-widget-ucaddon_ue_unfold\" data-id=\"ab9f111\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"ucaddon_ue_unfold.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<!-- start Unfold Content -->\n\t\t<link id='font-awesome-css' href='https:\/\/tirzepatyd.eu\/wp-content\/plugins\/unlimited-elements-for-elementor-premium\/assets_libraries\/font-awesome6\/fontawesome-all.min.css' type='text\/css' rel='stylesheet' >\n\t\t<link id='font-awesome-4-shim-css' href='https:\/\/tirzepatyd.eu\/wp-content\/plugins\/unlimited-elements-for-elementor-premium\/assets_libraries\/font-awesome6\/fontawesome-v4-shims.min.css' type='text\/css' rel='stylesheet' >\n\n<style>\/* widget: Unfold Content *\/\n\n#uc_ue_unfold_elementor_ab9f111{\n opacity: 0;\n transition: opacity .2s;\n}\n\n#uc_ue_unfold_elementor_ab9f111.ue-full-opacity{\n opacity: 1;\n}\n\n#uc_ue_unfold_elementor_ab9f111 .unfold_wrapper{\n  max-height:100%;\n  width: 100%;\n}\n\n#uc_ue_unfold_elementor_ab9f111 .unfold_card{\n  position: relative;\n  overflow:hidden;\n}\n\n#uc_ue_unfold_elementor_ab9f111 .uf_overlayuc_ue_unfold_elementor_ab9f111{\n    position: absolute;\n    right: 0;\n    bottom: 0;\n    left: 0;\n    z-index: 1;\n    background: -moz-linear-gradient(0deg, #ffffff) 10%, rgba(255, 255, 255, 0) 100%);\n    background: -webkit-linear-gradient(0deg, #ffffff 10%, rgba(255, 255, 255, 0) 100%);\n    background: linear-gradient(0deg, #ffffff 10%, rgba(255, 255, 255, 0) 100%);\n}\n\n#uc_ue_unfold_elementor_ab9f111 .ue-btn-wrap{\n        display: flex;   \n    position:relative;\n  z-index:2;\n}\n\n#uc_ue_unfold_elementor_ab9f111 #button_uc_ue_unfold_elementor_ab9f111{\n    display: flex;\n    justify-content: center;\n    align-items: center;\n    cursor:pointer;\n    transition:0.3s;\n}\n\n#uc_ue_unfold_elementor_ab9f111 .ue_unfold_title,\n#uc_ue_unfold_elementor_ab9f111 .ue-txt{\n  transition: all .3s ease;\n}\n\n.ue-btn-icon{\n  line-height:1em;\n}\n\n.ue-btn-icon svg{\n  height:1em;\n  width:1em;\n}\n\n#uc_ue_unfold_elementor_ab9f111 .unfold_wrapper{\n  overflow:hidden;\n  transition:300ms;\n}\n\n#uf_overlayuc_ue_unfold_elementor_ab9f111{\n  transition:300ms;\n}\n\n#uc_ue_unfold_elementor_ab9f111 .unfold_wrapper.ue-unfold-active #uf_overlayuc_ue_unfold_elementor_ab9f111{\n  height:0px;\n}\n\n#ue-icon-unfolded-uc_ue_unfold_elementor_ab9f111{\n  display:none;\n}\n\n#ue-text-unfolded-uc_ue_unfold_elementor_ab9f111{\n  display:none;\n}\n\n#uc_ue_unfold_elementor_ab9f111  button{\n  outline:none;\n}\n\n<\/style>\n\n\n<div id=\"uc_ue_unfold_elementor_ab9f111\" data-scroll-back=\"true\">\n  \n  \n  <div class=\"unfold_card\">\n    <div class=\"unfold_wrapper\" id=\"unfold_wrapper_uc_ue_unfold_elementor_ab9f111\">\n      <div class=\"uf_overlayuc_ue_unfold_elementor_ab9f111 uf_overlay\" id=\"uf_overlayuc_ue_unfold_elementor_ab9f111\"><\/div>\n                          <div class=\"ue-txt\"><div class=\"elementor-element elementor-element-e20e02e elementor-widget elementor-widget-text-editor\" data-id=\"e20e02e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><div class=\"elementor-element elementor-element-d08f889 elementor-widget elementor-widget-text-editor\" data-id=\"d08f889\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><section class=\"elementor-section elementor-top-section elementor-element elementor-element-4e0cfc7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4e0cfc7\" data-element_type=\"section\"><div class=\"elementor-container elementor-column-gap-default\"><div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-efa4c37\" data-id=\"efa4c37\" data-element_type=\"column\"><div class=\"elementor-widget-wrap elementor-element-populated\"><div class=\"elementor-element elementor-element-d97df69 elementor-widget elementor-widget-text-editor\" data-id=\"d97df69\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><p>The following compounds are advanced modulators of metabolic pathways studied in the context of their effects on receptors <strong>GLP-1<\/strong>, <strong>GIP<\/strong> i <strong>glucagon<\/strong>. Research highlights differences in potency, receptor selectivity and metabolic response dynamics.<\/p><p><strong>1. thirzepatide<\/strong><\/p><p><strong>The most important effects observed in the study<\/strong><\/p><ul><li>strong activation of GLP-1 and GIP receptors, which translates into a pronounced synergistic effect, according to the study,<\/li><li>pronounced effect on appetite and satiety regulation,<\/li><li>Significant improvement in glucose parameters in experimental models,<\/li><li>Beneficial effects on lipid metabolism.<\/li><\/ul><p><strong>How does it work?<\/strong><\/p><p>Thiogastatide is a dual agonist (dual-targeted peptide). Publications have shown that simultaneous activation of GLP-1 and GIP enhances signals responsible for regulating energy metabolism more than selective GLP-1 agonists. Studies have also shown that its action improves metabolic sensitivity and reduces energy intake in animal and cellular models.<\/p><p><strong>2. retatrutide<\/strong><\/p><p><strong>The most important effects observed in the study<\/strong><\/p><ul><li>simultaneous activation of as many as three receptors: GLP-1, GIP and glucagon,<\/li><li>stronger metabolic effect than dual-activation compounds,<\/li><li>Increased energy burn and higher thermogenic effect in experimental models,<\/li><li>Effect on improving lipid profile.<\/li><\/ul><p><strong>How does it work?<\/strong><\/p><p>Retatrutide is a so-called triple agonist, or tri-receptor modulator. In preclinical and early clinical studies, activation of the glucagon receptor has been shown to increase energy expenditure, and combining this with GLP-1 and GIP results in the most potent metabolic effect among incretin analogs known to date. Scientific studies highlight its prolonged duration of activity and high potency.<\/p><p><strong>3. semaglutide<\/strong><\/p><p><strong>The most important effects observed in the study<\/strong><\/p><ul><li>Highly selective GLP-1 receptor activation,<\/li><li>Significantly reduced appetite and increased satiety in experimental models,<\/li><li>Improving glycemic control,<\/li><li>Very long duration of action due to the stability of the molecule.<\/li><\/ul><p><strong>How does it work?<\/strong><\/p><p>Semaglutide is a classical, potent GLP-1 agonist with prolonged activity. In research studies, it shows a consistent, predictable action profile due to structural modifications that increase its binding to albumin. It is widely used as a reference (\"gold standard\") for comparative studies with newer multi-receptor agonists.<\/p><p><strong>4. orforglipron<\/strong><\/p><p><strong>The most important effects observed in the study<\/strong><\/p><ul><li>Strong agonist activation of GLP-1 while maintaining the small-molecule (non-peptide) form,<\/li><li>greater bioavailability compared to classical peptides,<\/li><li>Potentially faster dynamics of action,<\/li><li>Modulation of satiety and postprandial metabolic parameters.<\/li><\/ul><p><strong>How does it work?<\/strong><\/p><p>Orforglipron (formerly LY3502970) is one of the first non-peptide GLP-1 agonists. Unlike typical peptides, it is a stable small molecule, which gives it a unique pharmacokinetic profile. Studies show effects similar to classic GLP-1 agonists, but with different pharmacodynamics, making it an interesting tool for new research models.<\/p><p><strong>Comparison based on scientific sources<\/strong><\/p><table><thead><tr><th>Substance<\/th><th>Mechanism<\/th><th>The strongest action (according to studies)<\/th><th>Key feature<\/th><\/tr><\/thead><tbody><tr><td><strong>Tirzepatide<\/strong><\/td><td>GLP-1 + GIP<\/td><td>Strong satiety effect and reduction of energy intake<\/td><td>Synergistic dual activation<\/td><\/tr><tr><td><strong>Retatrutide<\/strong><\/td><td>GLP-1 + GIP + Glucagon<\/td><td>Highest energy consumption, strong metabolic impact<\/td><td>Triple agonist - widest receptor profile<\/td><\/tr><tr><td><strong>Semaglutide<\/strong><\/td><td>GLP-1<\/td><td>Stable, predictable metabolic effect<\/td><td>Single activation<\/td><\/tr><tr><td><strong>Orforglipron<\/strong><\/td><td>GLP-1 (non-peptide)<\/td><td>High bioavailability and different pharmacokinetics<\/td><td>Small molecule - unique mechanism of action<\/td><\/tr><\/tbody><\/table><hr \/><\/div><\/div><\/div><\/div><\/div><\/section><\/div><\/div><\/div><\/div><\/div>\n            <\/div>\n  \n      <div class=\"ue-btn-wrap\" id=\"btn_wrapper btn_wrapper_uc_ue_unfold_elementor_ab9f111\"> \n    <a href=\"javascript:void(0)\" role=\"button\" class=\"ubfold_btn\" id=\"button_uc_ue_unfold_elementor_ab9f111\">\n              <span class=\"ue-btn-icon\" id=\"ue-icon-folded-uc_ue_unfold_elementor_ab9f111\"><i class='fas fa-angle-down'><\/i><\/span>\n        <span class=\"ue-btn-icon\" id=\"ue-icon-unfolded-uc_ue_unfold_elementor_ab9f111\"><i class='fas fa-angle-up'><\/i><\/span>\n            <span id=\"ue-text-folded-uc_ue_unfold_elementor_ab9f111\">Read more<\/span>\n      <span id=\"ue-text-unfolded-uc_ue_unfold_elementor_ab9f111\">Read less<\/span>\n    <\/a>\n  <\/div>\n\t\n  \n  <\/div>\n  <\/div>\n<!-- end Unfold Content -->\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0167030 e-flex e-con-boxed e-con e-parent\" data-id=\"0167030\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-795ca6a e-con-full e-flex elementor-invisible e-con e-child\" data-id=\"795ca6a\" data-element_type=\"container\" data-settings=\"{&quot;animation&quot;:&quot;fadeIn&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-6740063 e-con-full e-flex e-con e-child\" data-id=\"6740063\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-64cc5ef e-con-full e-flex e-con e-child\" data-id=\"64cc5ef\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9e88f93 elementor-widget elementor-widget-image\" data-id=\"9e88f93\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/12\/tirze-e1751526038397.png\" title=\"\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ea2f262 elementor-widget__width-inherit elementor-widget elementor-widget-counter\" data-id=\"ea2f262\" data-element_type=\"widget\" data-widget_type=\"counter.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-counter\">\n\t\t\t<div class=\"elementor-counter-title\">GLP-1+GIP chart<\/div>\t\t\t<div class=\"elementor-counter-number-wrapper\">\n\t\t\t\t<span class=\"elementor-counter-number-prefix\"><\/span>\n\t\t\t\t<span class=\"elementor-counter-number\" data-duration=\"2000\" data-to-value=\"25\" data-from-value=\"0\">0<\/span>\n\t\t\t\t<span class=\"elementor-counter-number-suffix\">kg<\/span>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b9f8419 e-con-full e-flex e-con e-child\" data-id=\"b9f8419\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8243c1a elementor-widget elementor-widget-image\" data-id=\"8243c1a\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" src=\"https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/12\/semag-e1751526052912.png\" title=\"\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c025bff elementor-widget__width-inherit elementor-widget elementor-widget-counter\" data-id=\"c025bff\" data-element_type=\"widget\" data-widget_type=\"counter.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-counter\">\n\t\t\t<div class=\"elementor-counter-title\">GLP-1 chart<\/div>\t\t\t<div class=\"elementor-counter-number-wrapper\">\n\t\t\t\t<span class=\"elementor-counter-number-prefix\"><\/span>\n\t\t\t\t<span class=\"elementor-counter-number\" data-duration=\"2000\" data-to-value=\"10\" data-from-value=\"0\">0<\/span>\n\t\t\t\t<span class=\"elementor-counter-number-suffix\">kg<\/span>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0749d08 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"0749d08\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7ef5c51 elementor-widget elementor-widget-text-editor\" data-id=\"7ef5c51\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><div class=\"elementor-element elementor-element-10f08cd elementor-widget elementor-widget-text-editor\" data-id=\"10f08cd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><p>Tirzepatide research - <a href=\"https:\/\/tirzepatyd.eu\/en\/product\/tirzepatide\/\">\u00a0products<\/a> is characterized by high quality, as confirmed by the above studies. In addition, its performance has been confirmed in <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34170647\/\">research<\/a> clinical trials involving diabetics, highlighting the high efficacy of GLP 1 + GIP.\u00a0<\/p><\/div><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0b37699 e-con-full e-flex e-con e-child\" data-id=\"0b37699\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-aa8db34 elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"aa8db34\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">GLP\/GIp\/Glucagon what effects does it have?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ae4e2f1 elementor-invisible elementor-widget elementor-widget-ucaddon_ue_unfold\" data-id=\"ae4e2f1\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeIn&quot;}\" data-widget_type=\"ucaddon_ue_unfold.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n<!-- start Unfold Content -->\n\n<style>\/* widget: Unfold Content *\/\n\n#uc_ue_unfold_elementor_ae4e2f1{\n opacity: 0;\n transition: opacity .2s;\n}\n\n#uc_ue_unfold_elementor_ae4e2f1.ue-full-opacity{\n opacity: 1;\n}\n\n#uc_ue_unfold_elementor_ae4e2f1 .unfold_wrapper{\n  max-height:100%;\n  width: 100%;\n}\n\n#uc_ue_unfold_elementor_ae4e2f1 .unfold_card{\n  position: relative;\n  overflow:hidden;\n}\n\n#uc_ue_unfold_elementor_ae4e2f1 .uf_overlayuc_ue_unfold_elementor_ae4e2f1{\n    position: absolute;\n    right: 0;\n    bottom: 0;\n    left: 0;\n    z-index: 1;\n    background: -moz-linear-gradient(0deg, #ffffff) 10%, rgba(255, 255, 255, 0) 100%);\n    background: -webkit-linear-gradient(0deg, #ffffff 10%, rgba(255, 255, 255, 0) 100%);\n    background: linear-gradient(0deg, #ffffff 10%, rgba(255, 255, 255, 0) 100%);\n}\n\n#uc_ue_unfold_elementor_ae4e2f1 .ue-btn-wrap{\n        display: flex;   \n    position:relative;\n  z-index:2;\n}\n\n#uc_ue_unfold_elementor_ae4e2f1 #button_uc_ue_unfold_elementor_ae4e2f1{\n    display: flex;\n    justify-content: center;\n    align-items: center;\n    cursor:pointer;\n    transition:0.3s;\n}\n\n#uc_ue_unfold_elementor_ae4e2f1 .ue_unfold_title,\n#uc_ue_unfold_elementor_ae4e2f1 .ue-txt{\n  transition: all .3s ease;\n}\n\n.ue-btn-icon{\n  line-height:1em;\n}\n\n.ue-btn-icon svg{\n  height:1em;\n  width:1em;\n}\n\n#uc_ue_unfold_elementor_ae4e2f1 .unfold_wrapper{\n  overflow:hidden;\n  transition:300ms;\n}\n\n#uf_overlayuc_ue_unfold_elementor_ae4e2f1{\n  transition:300ms;\n}\n\n#uc_ue_unfold_elementor_ae4e2f1 .unfold_wrapper.ue-unfold-active #uf_overlayuc_ue_unfold_elementor_ae4e2f1{\n  height:0px;\n}\n\n#ue-icon-unfolded-uc_ue_unfold_elementor_ae4e2f1{\n  display:none;\n}\n\n#ue-text-unfolded-uc_ue_unfold_elementor_ae4e2f1{\n  display:none;\n}\n\n#uc_ue_unfold_elementor_ae4e2f1  button{\n  outline:none;\n}\n\n<\/style>\n\n\n<div id=\"uc_ue_unfold_elementor_ae4e2f1\" data-scroll-back=\"true\">\n  \n  \n  <div class=\"unfold_card\">\n    <div class=\"unfold_wrapper\" id=\"unfold_wrapper_uc_ue_unfold_elementor_ae4e2f1\">\n      <div class=\"uf_overlayuc_ue_unfold_elementor_ae4e2f1 uf_overlay\" id=\"uf_overlayuc_ue_unfold_elementor_ae4e2f1\"><\/div>\n                          <div class=\"ue-txt\"><div class=\"elementor-element elementor-element-7ef5c51 elementor-widget elementor-widget-text-editor\" data-id=\"7ef5c51\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><div class=\"elementor-element elementor-element-10f08cd elementor-widget elementor-widget-text-editor\" data-id=\"10f08cd\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><div class=\"elementor-element elementor-element-084aebc elementor-widget elementor-widget-text-editor\" data-id=\"084aebc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><section class=\"elementor-section elementor-top-section elementor-element elementor-element-4e0cfc7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4e0cfc7\" data-element_type=\"section\"><div class=\"elementor-container elementor-column-gap-default\"><div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-efa4c37\" data-id=\"efa4c37\" data-element_type=\"column\"><div class=\"elementor-widget-wrap elementor-element-populated\"><div class=\"elementor-element elementor-element-d97df69 elementor-widget elementor-widget-text-editor\" data-id=\"d97df69\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\"><div class=\"elementor-widget-container\"><p data-start=\"132\" data-end=\"722\">Latest<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9268041\/\"> research<\/a> confirm that a new formulation, approved by the U.S. Food and Drug Administration (FDA), can significantly help people who are overweight or obese. With regular intake of this peptide, healthy individuals have the potential to reduce up to a quarter of their initial body weight. Significantly, these effects are comparable to those obtained through bariatric surgery, while the therapy did not require drastic changes in patients' daily lifestyles. Of course, better eating habits and physical activity can further enhance the results.<\/p><p data-start=\"724\" data-end=\"1172\">In a large study involving 2,500 people without type 1 diabetes, researchers observed spectacular results. More than 60% participants, who took doses of 5 to 15 mg for more than a year, managed to reduce their body weight by a minimum of 20%. In some patients, the weight loss was even 22.5-25%, which in practice meant a weight loss of about 28 kilograms. <a href=\"https:\/\/www.mdpi.com\/2673-4168\/5\/2\/26\">Results<\/a> these show that the formulation can be an attractive option for people who care about their figure and health.<\/p><p data-start=\"106\" data-end=\"405\">Thiopeptide is a cutting-edge drug that is changing the approach to treating type 2 diabetes and overweight. This innovative peptide acts on the body in a complex way, activating two key gut hormones - GLP-1 and GIP - responsible for both blood glucose regulation and appetite control.<\/p><p data-start=\"407\" data-end=\"717\">Thanks to its unique chemical structure, tirzepatyd induces a quick sense of satiety after a meal, while stabilizing blood sugar levels. This makes both maintaining normal glucose levels and reducing weight easier, making it a valuable tool in weight loss therapy.<\/p><p data-start=\"719\" data-end=\"1085\">Previous studies indicate that tirzepatyd is superior to classical treatments in terms of efficacy, and is convenient to use. It is particularly helpful for people who are overweight or obese. Administered once a week, it acts on GLP-1 and GIP receptors, leading to a reduction in appetite, accelerated metabolism and gradual weight loss.<\/p><p data-start=\"1087\" data-end=\"1344\">The secret of tirzepatydu lies in its ability to mimic the natural gut hormones released after eating. It slows gastric emptying and amplifies satiety signals sent to the hypothalamus, which helps effectively reduce the amount of food consumed.<\/p><p data-start=\"1346\" data-end=\"1601\">Thirzepatide brings a new quality to the treatment of diabetes and weight problems, offering patients more effective and convenient solutions. It enables better control of sugar levels, curbing appetite and achieving a healthier body weight.<br \/>Source:<br \/><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33325008\/\">The Role of Tirzepatide, Dual GIP and GLP-1 Receptor Agonist, in the Management of Type 2 Diabetes: The SURPASS Clinical Trials<\/a><\/p><\/div><\/div><\/div><\/div><\/div><\/section><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n            <\/div>\n  \n      <div class=\"ue-btn-wrap\" id=\"btn_wrapper btn_wrapper_uc_ue_unfold_elementor_ae4e2f1\"> \n    <a href=\"javascript:void(0)\" role=\"button\" class=\"ubfold_btn\" id=\"button_uc_ue_unfold_elementor_ae4e2f1\">\n              <span class=\"ue-btn-icon\" id=\"ue-icon-folded-uc_ue_unfold_elementor_ae4e2f1\"><i class='fas fa-angle-down'><\/i><\/span>\n        <span class=\"ue-btn-icon\" id=\"ue-icon-unfolded-uc_ue_unfold_elementor_ae4e2f1\"><i class='fas fa-angle-up'><\/i><\/span>\n            <span id=\"ue-text-folded-uc_ue_unfold_elementor_ae4e2f1\">Read more<\/span>\n      <span id=\"ue-text-unfolded-uc_ue_unfold_elementor_ae4e2f1\">Read less<\/span>\n    <\/a>\n  <\/div>\n\t\n  \n  <\/div>\n  <\/div>\n<!-- end Unfold Content -->\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Tirzepatyd &#8211; jak to dzia\u0142a? Peptydowi agoni\u015bci receptor\u00f3w inkretynowych Poni\u017csze zwi\u0105zki to zaawansowane modulatory szlak\u00f3w metabolicznych badane w kontek\u015bcie ich wp\u0142ywu na receptory GLP-1, GIP i glukagonu. W badaniach naukowych zwraca si\u0119 uwag\u0119 na r\u00f3\u017cnice w sile dzia\u0142ania, selektywno\u015bci receptorowej oraz dynamice odpowiedzi metabolicznej. 1. Tirzepatyd Najwa\u017cniejsze efekty obserwowane w badaniach silna aktywacja receptor\u00f3w GLP-1 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":21458,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-11835","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/pages\/11835","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/comments?post=11835"}],"version-history":[{"count":0,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/pages\/11835\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/media\/21458"}],"wp:attachment":[{"href":"https:\/\/tirzepatyd.eu\/en\/wp-json\/wp\/v2\/media?parent=11835"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}