{"id":18845,"date":"2024-05-26T20:59:43","date_gmt":"2024-05-26T18:59:43","guid":{"rendered":"https:\/\/tirzepatyd.eu\/?post_type=product&#038;p=18845"},"modified":"2026-04-18T11:23:44","modified_gmt":"2026-04-18T09:23:44","slug":"tirzepatide-10-mg","status":"publish","type":"product","link":"https:\/\/tirzepatyd.eu\/cs\/obchod-produkt\/tirzepatide-10-mg\/","title":{"rendered":"GLP1+GIP 10 mg injek\u010dn\u00ed lahvi\u010dka"},"content":{"rendered":"<div data-elementor-type=\"product-post\" data-elementor-id=\"18845\" class=\"elementor elementor-18845\" data-elementor-post-type=\"product\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d58fc76 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d58fc76\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2c501af\" data-id=\"2c501af\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8cd3e97 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"8cd3e97\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<h2 data-start=\"634\" data-end=\"700\">Tirzepatid 10 mg - mechanismus \u00fa\u010dinku a metabolick\u00fd v\u00fdznam<\/h2><p data-start=\"740\" data-end=\"950\"><span class=\"hover:entity-accent entity-underline inline cursor-pointer align-baseline\"><span class=\"whitespace-normal\">Tirzepatid 10 mg<\/span><\/span> je syntetick\u00fd peptidov\u00fd analog navr\u017een\u00fd jako du\u00e1ln\u00ed agonista receptor\u016f GIPR a GLP-1R, kter\u00e9 pat\u0159\u00ed do skupiny receptor\u016f sp\u0159a\u017een\u00fdch s G proteinem (GPCR).<\/p><p data-start=\"952\" data-end=\"1012\">Ve v\u00fdzkumn\u00fdch modelech vede aktivace t\u011bchto receptor\u016f k:<\/p><ul><li data-start=\"1016\" data-end=\"1064\">zv\u00fd\u0161en\u00ed intracelul\u00e1rn\u00ed koncentrace cAMP,<\/li><li data-start=\"1067\" data-end=\"1123\">Zv\u00fd\u0161en\u00e1 inzulinotropn\u00ed odpov\u011b\u010f z\u00e1visl\u00e1 na gluk\u00f3ze,<\/li><li data-start=\"1126\" data-end=\"1157\">modulace sekrece glukagonu,<\/li><li data-start=\"1160\" data-end=\"1198\">vliv na rychlost vyprazd\u0148ov\u00e1n\u00ed \u017ealudku,<\/li><li data-start=\"1201\" data-end=\"1260\">\u00fa\u010dinky na centr\u00e1ln\u00ed mechanismy reguluj\u00edc\u00ed chu\u0165 k j\u00eddlu.<\/li><\/ul><p data-start=\"1262\" data-end=\"1424\">Du\u00e1ln\u00ed aktivace osy GIP\/GLP-1 je v literatu\u0159e interpretov\u00e1na jako synergick\u00fd \u00fa\u010dinek, kter\u00fd integruje regulaci glyk\u00e9mie a energetick\u00e9 rovnov\u00e1hy.<\/p><hr data-start=\"1426\" data-end=\"1429\" \/><h2 data-start=\"1431\" data-end=\"1487\">Vliv na parametry t\u011blesn\u00e9 hmotnosti v klinick\u00fdch studi\u00edch<\/h2><p data-start=\"1489\" data-end=\"1631\">Ve studijn\u00edm programu SURMOUNT-1 (72 t\u00fddn\u016f sledov\u00e1n\u00ed) bylo p\u0159i d\u00e1vce 10 mg zaznamen\u00e1no pr\u016fm\u011brn\u00e9 sn\u00ed\u017een\u00ed hmotnosti p\u0159ibli\u017en\u011b o 19-20%.<\/p><p data-start=\"1633\" data-end=\"1656\">Soub\u011b\u017en\u011b byla prov\u00e1d\u011bna pozorov\u00e1n\u00ed:<\/p><ul><li data-start=\"1660\" data-end=\"1699\">zlep\u0161en\u00ed ukazatel\u016f inzul\u00ednov\u00e9 rezistence,<\/li><li data-start=\"1702\" data-end=\"1736\">p\u0159\u00edzniv\u00e9 zm\u011bny v lipidogramu,<\/li><li data-start=\"1739\" data-end=\"1763\">sn\u00ed\u017een\u00ed obvodu pasu,<\/li><li data-start=\"1766\" data-end=\"1799\">stabilizace glykemick\u00fdch parametr\u016f.<\/li><\/ul><p data-start=\"1801\" data-end=\"1916\">Srovn\u00e1vac\u00ed anal\u00fdzy uk\u00e1zaly v\u011bt\u0161\u00ed sn\u00ed\u017een\u00ed HbA1c a t\u011blesn\u00e9 hmotnosti ne\u017e u selektivn\u00edho agonismu GLP-1.<\/p><hr data-start=\"1918\" data-end=\"1921\" \/><h2 data-start=\"1923\" data-end=\"1950\">Farmakodynamick\u00fd profil<\/h2><p data-start=\"1952\" data-end=\"2141\">D\u00e1vka 10 mg je d\u016fle\u017eit\u00fdm referen\u010dn\u00edm bodem pro anal\u00fdzu pom\u011bru d\u00e1vky a \u00fa\u010dinku a umo\u017e\u0148uje posoudit intenzitu metabolick\u00e9 odpov\u011bdi a toleranci v podm\u00ednk\u00e1ch kontrolovan\u00fdch studi\u00ed.<\/p><p data-start=\"2143\" data-end=\"2272\">V klinick\u00fdch studi\u00edch byly nej\u010dast\u011bji hl\u00e1\u0161eny gastrointestin\u00e1ln\u00ed ne\u017e\u00e1douc\u00ed \u00fa\u010dinky z\u00e1visl\u00e9 na d\u00e1vce.<\/p><hr data-start=\"2663\" data-end=\"2666\" \/><h2 data-start=\"2668\" data-end=\"2689\">Povaha v\u00fdrobku<\/h2><p data-start=\"2691\" data-end=\"2787\">Tirzepatid 10 mg nab\u00edzen\u00fd na laboratorn\u00edm trhu je referen\u010dn\u00ed materi\u00e1l pro v\u00fdzkum:<\/p><ul data-start=\"2789\" data-end=\"2926\"><li data-start=\"2789\" data-end=\"2831\"><p data-start=\"2791\" data-end=\"2831\">signalizace inkretinov\u00fdch receptor\u016f,<\/p><\/li><li data-start=\"2832\" data-end=\"2867\"><p data-start=\"2834\" data-end=\"2867\">metabolismus gluk\u00f3zy a lipid\u016f,<\/p><\/li><li data-start=\"2868\" data-end=\"2905\"><p data-start=\"2870\" data-end=\"2905\">regulace energetick\u00e9 bilance,<\/p><\/li><li data-start=\"2906\" data-end=\"2926\"><p data-start=\"2908\" data-end=\"2926\">Mechanismy GPCR.<\/p><\/li><\/ul><p data-start=\"2928\" data-end=\"3004\">Produkt je ur\u010den pouze pro v\u00fdzkumn\u00e9 \u00fa\u010dely (Research Use Only).<\/p><hr data-start=\"2644\" data-end=\"2647\" \/><h2 data-start=\"2649\" data-end=\"2696\">Tirzepatide 10 mg online dostupnost a kde koupit informace<\/h2><ul data-start=\"2698\" data-end=\"3135\"><li data-start=\"2698\" data-end=\"2862\"><p data-start=\"2700\" data-end=\"2862\">Tirzepatid 10 mg je k dispozici <strong data-start=\"2732\" data-end=\"2756\">pouze na l\u00e9ka\u0159sk\u00fd p\u0159edpis<\/strong> ve stacion\u00e1rn\u00edch l\u00e9k\u00e1rn\u00e1ch a online l\u00e9k\u00e1rn\u00e1ch s leg\u00e1ln\u00edm prodejem l\u00e9k\u016f na p\u0159edpis.<\/p><\/li><li data-start=\"2863\" data-end=\"2959\"><p data-start=\"2865\" data-end=\"2959\">\u00a0Thirzepatid je tak\u00e9 k dispozici pot\u0159ebuje <strong data-start=\"150\" data-end=\"194\">v\u011bdeck\u00fd v\u00fdzkum a laboratorn\u00ed pou\u017eit\u00ed<\/strong>. Nen\u00ed ur\u010den k samol\u00e9\u010db\u011b ani k dom\u00e1c\u00edmu pou\u017eit\u00ed.<\/p><\/li><li data-start=\"2960\" data-end=\"3135\"><p data-start=\"2962\" data-end=\"3135\">V n\u011bkter\u00fdch zem\u00edch m\u016f\u017ee b\u00fdt p\u0159\u00edstup k p\u0159\u00edpravku regulov\u00e1n prost\u0159ednictv\u00edm seznamu hrazen\u00fdch l\u00e9k\u016f nebo po\u017eadavkem na p\u0159edchoz\u00ed l\u00e9\u010dbu jin\u00fdmi metodami (dieta, fyzick\u00e1 aktivita).<\/p><\/li><\/ul><hr data-start=\"3137\" data-end=\"3140\" \/><h2 data-start=\"3142\" data-end=\"3194\">Tirzepatid 10 mg srovn\u00e1n\u00ed s jin\u00fdmi peptidy<\/h2><ul data-start=\"3196\" data-end=\"3658\"><li data-start=\"3196\" data-end=\"3343\"><p data-start=\"3198\" data-end=\"3343\"><a href=\"https:\/\/tirzepatyd.eu\/cs\/obchod-produkt\/semaglutid-2-mg-injekcni-lahvicka\/\"><strong data-start=\"3198\" data-end=\"3213\">Semaglutid<\/strong><\/a>: p\u016fsob\u00ed pouze na receptor GLP-1, \u00fa\u010dinnost p\u0159i hubnut\u00ed je pr\u016fm\u011brn\u00e1 ~15%, pou\u017e\u00edv\u00e1 se p\u0159i l\u00e9\u010db\u011b diabetu 2. typu a obezity.<\/p><\/li><li data-start=\"3344\" data-end=\"3476\"><p data-start=\"3346\" data-end=\"3476\"><strong data-start=\"3346\" data-end=\"3361\">Tirzepatid<\/strong>: du\u00e1ln\u00ed mechanismus (GLP-1 + GIP), \u00fa\u010dinnost p\u0159i \u00fabytku hmotnosti ~20-25% a zlep\u0161en\u00ed kontroly glyk\u00e9mie.<\/p><\/li><li data-start=\"3477\" data-end=\"3658\"><p data-start=\"3479\" data-end=\"3658\"><a href=\"https:\/\/tirzepatyd.eu\/cs\/obchod-produkt\/glp-3-retatrutid-4mg-injekcni-lahvicka\/\"><strong data-start=\"3479\" data-end=\"3494\">Retatrutid<\/strong><\/a>: Experiment\u00e1ln\u00ed trojit\u00fd peptid (GLP-1 + GIP + glukagonov\u00fd receptor), p\u0159edb\u011b\u017en\u00e9 studie nazna\u010duj\u00ed velmi vysokou redukci hmotnosti, st\u00e1le ve f\u00e1zi klinick\u00fdch zkou\u0161ek.<\/p><\/li><\/ul><p data-start=\"3660\" data-end=\"3861\">Tirzepatid 10 mg se vyzna\u010duje t\u00edm, \u017ee kombinuje <strong data-start=\"3699\" data-end=\"3755\">Vysoce \u00fa\u010dinn\u00e9 sni\u017eov\u00e1n\u00ed hmotnosti s kontrolou glyk\u00e9mie<\/strong> a je k dispozici v t\u00fddenn\u00edch d\u00e1vk\u00e1ch, tak\u017ee jeho u\u017e\u00edv\u00e1n\u00ed je ve srovn\u00e1n\u00ed s jin\u00fdmi peptidy pohodln\u011bj\u0161\u00ed.<\/p><hr data-start=\"3137\" data-end=\"3140\" \/><p data-start=\"3660\" data-end=\"3861\"><a href=\"https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/10mg-0.5ml-Camera.png\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-medium wp-image-30658 aligncenter\" src=\"https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/10mg-0.5ml-Camera-300x225.png\" alt=\"Tirzepatid 10 mg injek\u010dn\u00ed lahvi\u010dka\" width=\"300\" height=\"225\" srcset=\"https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/10mg-0.5ml-Camera-300x225.png 300w, https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/10mg-0.5ml-Camera-800x600.png 800w, https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/10mg-0.5ml-Camera-64x48.png 64w, https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/10mg-0.5ml-Camera-768x576.png 768w, https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/10mg-0.5ml-Camera-16x12.png 16w, https:\/\/tirzepatyd.eu\/wp-content\/uploads\/2025\/09\/10mg-0.5ml-Camera.png 1024w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p><p>V\u00fdzkum a zdroje:<\/p><p><a href=\"https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(21)01324-6\/abstract\">\u00da\u010dinnost a bezpe\u010dnost nov\u00e9ho du\u00e1ln\u00edho receptoru GIP a GLP-1<\/a><\/p><p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36050763\/\">Thirzepatid, du\u00e1ln\u00ed receptor GIP\/GLP-1<\/a><\/p><hr data-start=\"3137\" data-end=\"3140\" \/><p><strong>V\u00fdrobek je ur\u010den pro v\u011bdeck\u00fd v\u00fdzkum a laboratorn\u00ed anal\u00fdzy. V\u0161echny \u010dl\u00e1nky a informace na t\u011bchto webov\u00fdch str\u00e1nk\u00e1ch slou\u017e\u00ed pouze k informa\u010dn\u00edm a vzd\u011bl\u00e1vac\u00edm \u00fa\u010del\u016fm.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p><strong data-start=\"118\" data-end=\"139\">Tirzepatid 10 mg<\/strong> je pokro\u010dil\u00fd syntetick\u00fd peptid s vysokou \u010distotou a du\u00e1ln\u00ed aktivitou v\u016f\u010di receptor\u016fm GIP a GLP-1, kter\u00fd se pou\u017e\u00edv\u00e1 v nejmodern\u011bj\u0161\u00edch v\u00fdzkumn\u00fdch projektech zam\u011b\u0159en\u00fdch na regulaci metabolismu a inkretinov\u00e9 mechanismy.<\/p>","protected":false},"featured_media":30658,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[124,111,15],"product_tag":[136],"class_list":["post-18845","product","type-product","status-publish","has-post-thumbnail","product_cat-produkty-w-fiolce","product_cat-glp1gip","product_cat-laboratory-research","product_tag-fiolka","first","instock","shipping-taxable","purchasable","product-type-variable"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO Pro 4.9.9 - aioseo.com -->\n\t<meta name=\"description\" content=\"Tirzepatide 10 mg in vial - dual GIP\/GLP-1 agonist peptide. 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